Red blood cell glycophorins.
نویسندگان
چکیده
منابع مشابه
A Comprehensive Review of Our Current Understanding of Red Blood Cell (RBC) Glycoproteins
Human red blood cells (RBC), which are the cells most commonly used in the study of biological membranes, have some glycoproteins in their cell membrane. These membrane proteins are band 3 and glycophorins A-D, and some substoichiometric glycoproteins (e.g., CD44, CD47, Lu, Kell, Duffy). The oligosaccharide that band 3 contains has one N-linked oligosaccharide, and glycophorins possess mostly O...
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Glycophorins are the major sialoglycoproteins in red blood cell membranes, possessing various physiological and pathological roles. We examined membrane glycoproteins in canine red cells and cloned cDNAs for two major glycophorins, glycophorins A (GPA) and C (GPC) from bone marrow cells. Periodic acid-Schiff staining and immunoblotting analyses showed that canine red cell membranes contained se...
متن کاملBabesia divergens and Plasmodium falciparum use common receptors, glycophorins A and B, to invade the human red blood cell.
Babesiosis has long been recognized as an economically important disease of cattle, but only in the last 30 years has Babesia been recognized as an important pathogen in humans. Invasion of erythrocytes is an integral part of the Babesia life cycle. However, very little information is available on the molecules involved in this process, in contrast to another hemoparasite, Plasmodium falciparum...
متن کاملSynthetic peptides homologous to human glycophorins of the Miltenberger complex of variants of MNSs blood group system specify the epitopes for Hil, SJL, Hop, and Mur antisera.
The antigenic epitopes of the MNSs blood groups are localized on alpha and delta glycophorins (glycophorins A and B) of the erythrocyte surface. Hil, SJL, Mur, and Hop antisera define the Miltenberger (Mi) complex of MiV, MiJ.L., MiIII, and MiVI variant serologic phenotypes of this blood group system. We report here the location of the epitopes for antibodies in these antisera. The antigens of ...
متن کاملChanges in human red blood cells during aging in vivo.
The human red blood cells survive in the circulation for 120 days. Density-gradient centrifugation technique is widely used to prepare red cell fractions of different ages. It has been known that various biochemical properties of the red cells change with aging in vivo. If the changes in the red cell surface lead to the destruction of senescent cells, it would be of interest to know how these c...
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عنوان ژورنال:
- Blood
دوره 80 8 شماره
صفحات -
تاریخ انتشار 1992